Abstract: Secondary induced bladder carcinoma after brachytherapy for prostate carcinoma is a clinically significant complication with a frequency ranging between 1.5% and 10.8% according to different studies[1-10]. The risk factors for the occurrence of this disease are numerous, some of them are the total radiation dose, the patient's age and smoking.

We present a case of an 84-year-old patient with secondarily induced bladder carcinoma (SICBC), diagnosed two years after brachytherapy (BT) for the treatment of prostate carcinoma. The patient was admitted for elective surgery due to a bladder stone, confirmed by imaging studies. During transurethral laser lithotripsy of the stone, a papillary tumor formation was also discovered, which was resected and sent for histological analysis. It is assumed that the tumor was secondarily induced as a result of the previous BT. The need for long-term follow-up of patients undergoing BT and the importance of a multidisciplinary approach in the diagnosis and treatment of secondarily induced neoplasms is of great importance.

Keywords: secondarily induced carcinoma, bladder, brachytherapy, prostate carcinoma, long-term follow-up

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